Q ONO-4059用途是什么？

Question time：6/21/2021 9:48:19 AM

Describe：ONO-4059是做什么用的?哪里可以用到ONO-4059?

A

admin 2021-06-30 13:02

ONO-4059一种有效的口服活性的BTK(布鲁顿酪氨酸激酶)抑制剂, IC50:2.2nM。Tirabrutinib is a potent and orally active Bruton agammaglobulinemia tyrosine kinase (BTK) in hibitor. Upon administration, ONO-4059 covalently binds to BTK within B cells, thereby preventing B-cell receptor