Q ARV-825用途是什么？

Question time：9/6/2021 9:23:23 AM

Describe：ARV-825是做什么用的?哪里可以用到ARV-825?

A

admin 2021-09-06 10:19

ARV-825一种BRD4抑制剂,对BRD4的BD1和BD2结构域具有高亲和力，Kd值分别为90和28nM。ARV-825 is a PROTAC (proteolysis-targeting chimera). ARV-825 exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells. Co-treat