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Q SEN 12333用途是什么？

Question time：8/19/2021 9:09:28 AM

Describe：SEN 12333是做什么用的?哪里可以用到SEN 12333?

A
admin 2021-08-19 09:09
SEN 12333 is a nicotinic acetylcholine receptor (nAChR) agonist. SEN 12333 displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAC hRs (IC50 = 8.5 渭M). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. SEN 12333 is a brain penetrant and orally bioavailable.

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