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Q 花椒毒素用途是什么?

Question time:6/30/2021 1:01:28 PM

Describe:花椒毒素是做什么用的?哪里可以用到花椒毒素?

A
admin 2021-08-19 09:09
花椒毒素用于治疗牛皮癣、白癫风等疾病;一种有效的CYP抑制剂。8-MOP is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). As a member of the foranocoumarins, 8-Methoxypsoralen has shown more potency than 5-MOP, 5-OH-P , DH-8-MOP and psoralen in the inhibiton of CYP2B1 (cytochrome P-450 2B1). Methoxsalen has been shown to completely inhibit the metabolism of nicotine (sc-212379) in vitro. The compound has been observed to inhibit the metabolism of theophylline、 caffeine、hexobarbital and phenytoin.;能与UVA照射诱导DNA中的单加合物和链间交联,来研究DNA修复和重组机制。

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