Q TP-0903游离态用途是什么？

Question time：6/30/2021 1:00:05 PM

Describe：TP-0903游离态是做什么用的?哪里可以用到TP-0903游离态?

A

admin 2021-06-30 13:00

TP-0903游离态一种高效性的、选择性的Axl受体酪氨酸激酶抑制剂，IC50：27nM。Dubermatinib is a potent and selective AXL inhibitor. TP-0903 induces massive apoptosis in CLL B cells with LD50 values of nanomolar ranges. Combination of TP-0903 with BTK inhibitors augments CLL B-cell apopto